Author's Reply: Salivary Gland Tumors

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Malignant salivary gland tumors

Salivary gland neoplasms are a heterogeneous and important group of tumors of the Oral and Maxillofacial Pathology. They comprise from 2 to 3% of all the salivary gland lesions and tumors1,2 because their heterogeneity, since several years, different classifications based in clinical or microscopic criteria had been appeared.3-7 The most recent and most widely used is that proposed by Seifert e...

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D-1 Gene Polymorphism in Salivary Gland Tumors

Objectives This study aimed to assess PD-1gene polymorphism in salivary gland tumors in patients referred to Khalili Hospital in Shiraz. Methods This case-control study evaluated 48 patients with salivary gland tumors and 100 age- and sex-matched healthy controls. First, 5cc blood samples were obtained from patients and transferred to vials containing anti-coagulated EDTA. DNA was extracted, a...

MTA1 Expression in Benign and Malignant Salivary gland Tumors

Introduction: Salivary gland tumors (SGTs) are important parts of human neoplasms. The most common SGT is pleomorphic adenoma and the most common malignant SGTs are mucoepidermoid carcinoma and adenoid cystic carcinoma (ACC). Metastasis-associated genes 1 (MTA1), a member of the nucleosome remodeling and histone deacetylation complex, is one newly discovered gene which recruits histone deacetyl...